Data to be Presented at EASL 2017 Highlighting GENFIT's Latest Progress in NASH Biomarker Diagnostics, Identifying Novel Compounds with Potent Antifibrotic Properties, and Illustrating the Opportunities in Anti-NASH Drug Combinations
Lille (France), Cambridge (Massachusetts, United States), April 5 th , 2017 - GENFIT (Euronext: GNFT - ISIN: FR0004163111), a biopharmaceutical company at the forefront of developing therapeutic and diagnostic solutions in metabolic and inflammatory diseases, that notably affect the liver or the gastrointestinal system, today announced it will present new data at the International Liver Congress 2017  , which will be held April 19-23 in Amsterdam, The Netherlands. The abstracts are available on the website of the Congress.
A first series of data will underline, via two abstracts, the Company's latest progress in its non invasive biomarker diagnostics in NASH. Data will also be presented on the discovery of nine miRNAs and their relevance in identifying NASH patients to be treated, and a simple diagnostic score for patients and monitoring of their disease.
The progress presented in a third abstract will support the rationale for the repurposing of nitazoxanide (NTZ), currently prescribed as an antiparisitic, in the treatment of different fibrotic disorders, including liver fibrosis.
A final abstract, presenting data on the therapeutic complementarity of elafibranor and an FXR agonist (exemplified with obeticholic acid), will illustrate the potential for new combination treatments with elafibranor for the best possible care of NASH patients.
The poster presentations:
From Thursday, April 20 to Saturday, April 22, 2017
Saturday, April 22, 2017
GENFIT participation at the International Liver Congress 2017:
GENFIT will host two events:
For more information please visit the EASL Annual Meeting website: https://ilc-congress.eu/
Elafibranor is GENFIT's lead pipeline product. Elafibranor is an oral once-daily treatment, and a first-in-class drug acting via dual peroxisome proliferator-activated alpha/delta pathways developed to treat, in particular, nonalcoholic steatohepatitis (NASH). Elafibranor is believed to address multiple facets of NASH, including inflammation, insulin sensitivity, lipid/metabolic profile, and liver markers.
"NASH", or nonalcoholic steatohepatitis, is a liver disease characterized by an accumulation of fat (lipid droplets), along with inflammation and degeneration of hepatocytes. The disease is associated with long term risk of progression to cirrhosis, a state where liver function is diminished, leading to liver insufficiency, and also progression to liver cancer.
GENFIT is a biopharmaceutical company focused on the discovery and development of drug candidates in areas of high unmet medical needs corresponding to a lack of suitable treatment and an increasing number of patients worldwide. GENFIT's R&D efforts are focused on bringing new medicines to market for patients with metabolic, inflammatory, autoimmune and fibrotic diseases, that affect the liver (such as NASH - Nonalcoholic steatohepatitis) and more generally the gastro-intestinal arena. GENFIT's approach combines novel treatments and biomarkers. Its lead proprietary compound, elafibranor, is currently in a Phase 3 study. With facilities in Lille and Paris, France, and Cambridge, MA (USA), the Company has approximately 130 employees. GENFIT is a public company listed in compartment B of Euronext's regulated market in Paris (Euronext: GNFT - ISIN: FR0004163111). www.genfit.com
Forward Looking Statement / Disclaimer:
This press release contains certain forward-looking statements. Although the Company believes its expectations are based on reasonable assumptions, these forward-looking statements are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those expressed in, or implied or projected by, the forward-looking statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, including related to biomarkers, progression of, and results of clinical data from, the RESOLVE-IT trial, review and approvals by regulatory authorities, such as the FDA or the EMA, regarding in particular, elafibranor in NASH and PBC, as well as other indications, and biomarkers, the success of any inlicensing strategies, the Company's continued ability to raise capital to fund its development, as well as those discussed or identified in the Company's public filings with the AMF, including those listed under Section 7 "Main Risks and Uncertainties" of the Company's Half Year 2016 Business and Financial Report, which is available on GENFIT's website ( www.genfit.com ) and on the website of the AMF ( http://www.amf-france.org ). Other than as required by applicable law, the Company does not undertake any obligation to update or revise any forward-looking information or statements.
This press release and the information contained herein do not constitute an offer to sell or a solicitation of an offer to buy or subscribe to shares in GENFIT in any country. This press release has been prepared in both French and English. In the event of any differences between the two texts, the French language version shall supersede.
GENFIT | Jean-François Mouney - Chairman & CEO | Ph. +333 2016 4000
MILESTONES - Press Relations | Bruno Arabian | Ph. +331 8362 3484 / +336 8788 4726 - firstname.lastname@example.org
GENFIT | 885 Avenue Eugène Avinée, 59120 Loos - FRANCE | +333 2016 4000 | www.genfit.com
 The 52 nd Annual Meeting of the European Association for the Study of the Liver (EASL)